Thymidine 5'-O-(1-thiotriphosphate) structure

Thymidine 5'-O-(1-thiotriphosphate)

TL;DR: Thymidine 5'-O-(1-thiotriphosphate) (CAS 83199-35-3) is a chemical compound with molecular formula C10H17N2O13P3S and molecular weight 497.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphinothioyl] phosphono hydrogen phosphate

Also Known As: Dttp alphas, dTTPalphaS, TTPalphaS, Dttp (alpha S), Sp-TTPalphaS

CAS: 83199-35-3
Molecular Formula C10H17N2O13P3S
Molecular Weight 497.97 g/mol
LogP -3.3
Topological Polar Surface Area 254.0 Ų
Hydrogen Bond Donors 6
Hydrogen Bond Acceptors 14
Rotatable Bonds 8
Exact Mass 497.96643
Heavy Atoms 29
Complexity 858.0

Chemical Identifiers

CAS Number 83199-35-3
SMILES CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O
InChIKey PXHHTOSRELKWOE-MXWQNOQOSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (1 patents) Biotechnology (16 patents) Heterocyclic Building Blocks (2 patents)

Product Overview

Thymidine 5'-O-(1-thiotriphosphate) (CAS 83199-35-3), with molecular formula C10H17N2O13P3S and molecular weight 497.97 g/mol. IUPAC: [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphinothioyl] phosphono hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thymidine 5'-O-(1-thiotriphosphate)

XLogP
-3.3
TPSA (Topological Polar Surface Area)
254.0
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
14
Rotatable Bonds
8
Heavy Atoms
29
Complexity
858.0
Exact Mass
497.96643
Monoisotopic Mass
497.96643
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thymidine 5'-O-(1-thiotriphosphate)

The XLogP value of -3.3 indicates that Thymidine 5'-O-(1-thiotriphosphate) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 254.0 Ų indicates high polarity, suggesting Thymidine 5'-O-(1-thiotriphosphate) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thymidine 5'-O-(1-thiotriphosphate) has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thymidine 5'-O-(1-thiotriphosphate)?

The CAS number of Thymidine 5'-O-(1-thiotriphosphate) is 83199-35-3.

What is the molecular formula of Thymidine 5'-O-(1-thiotriphosphate)?

The molecular formula of Thymidine 5'-O-(1-thiotriphosphate) is C10H17N2O13P3S.

What is the molecular weight of Thymidine 5'-O-(1-thiotriphosphate)?

The molecular weight of Thymidine 5'-O-(1-thiotriphosphate) is 497.97 g/mol.

Where can I buy Thymidine 5'-O-(1-thiotriphosphate)?

You can request a quote for Thymidine 5'-O-(1-thiotriphosphate) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thymidine 5'-O-(1-thiotriphosphate)?

Yes, KEHONG BIO provides custom synthesis services for Thymidine 5'-O-(1-thiotriphosphate) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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