N-(ethyl-2-diazomalonyl)thyroxine structure

N-(ethyl-2-diazomalonyl)thyroxine

TL;DR: N-(ethyl-2-diazomalonyl)thyroxine (CAS 83181-47-9) is a chemical compound with molecular formula C20H15I4N3O7 and molecular weight 916.71 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[(2-diazo-3-ethoxy-3-oxopropanoyl)amino]-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid

Also Known As: Edm-T4, N-(Ethyl-2-diazomalonyl)thyroxine, (2S)-2-[(2-diazo-3-ethoxy-3-oxopropanoyl)amino]-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid, L-Tyrosine, N-(2-diazo-3-ethoxy-1,3-dioxopropyl)-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, (E)-2-diazonio-1-ethoxy-3-[[(2S)-1-hydroxy-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-1-oxopropan-2-yl]amino]-3-oxoprop-1-en-1-olate

CAS: 83181-47-9
Molecular Formula C20H15I4N3O7
Molecular Weight 916.71 g/mol
LogP 6.4
Topological Polar Surface Area 124.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 8
Rotatable Bonds 10
Exact Mass 916.7089
Heavy Atoms 34
Complexity 789.0

Chemical Identifiers

CAS Number 83181-47-9
SMILES CCOC(=O)C(=[N+]=[N-])C(=O)N[C@@H](CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)C(=O)O
InChIKey XQCBTROWXKXLSP-AWEZNQCLSA-N

Product Overview

N-(ethyl-2-diazomalonyl)thyroxine (CAS 83181-47-9), with molecular formula C20H15I4N3O7 and molecular weight 916.71 g/mol. IUPAC: (2S)-2-[(2-diazo-3-ethoxy-3-oxopropanoyl)amino]-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of N-(ethyl-2-diazomalonyl)thyroxine

XLogP
6.4
TPSA (Topological Polar Surface Area)
124.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
8
Rotatable Bonds
10
Heavy Atoms
34
Complexity
789.0
Exact Mass
916.7089
Monoisotopic Mass
916.7089
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-(ethyl-2-diazomalonyl)thyroxine

The XLogP value of 6.4 indicates that N-(ethyl-2-diazomalonyl)thyroxine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 124.0 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(ethyl-2-diazomalonyl)thyroxine. Following Lipinski's Rule of Five, N-(ethyl-2-diazomalonyl)thyroxine has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N-(ethyl-2-diazomalonyl)thyroxine?

The CAS number of N-(ethyl-2-diazomalonyl)thyroxine is 83181-47-9.

What is the molecular formula of N-(ethyl-2-diazomalonyl)thyroxine?

The molecular formula of N-(ethyl-2-diazomalonyl)thyroxine is C20H15I4N3O7.

What is the molecular weight of N-(ethyl-2-diazomalonyl)thyroxine?

The molecular weight of N-(ethyl-2-diazomalonyl)thyroxine is 916.71 g/mol.

Where can I buy N-(ethyl-2-diazomalonyl)thyroxine?

You can request a quote for N-(ethyl-2-diazomalonyl)thyroxine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N-(ethyl-2-diazomalonyl)thyroxine?

Yes, KEHONG BIO provides custom synthesis services for N-(ethyl-2-diazomalonyl)thyroxine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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