4-Acetyl-5-(4-chlorophenyl)oxolan-2-one
TL;DR: 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one (CAS 83144-11-0) is a chemical compound with molecular formula C12H11ClO3 and molecular weight 238.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-acetyl-5-(4-chlorophenyl)oxolan-2-one
Also Known As: 4-acetyl-5-(4-chlorophenyl)oxolan-2-one, trans-4-Acetyl-5-(p-chlorophenyl)-4,5-dihydro-2(3H)-furanone, 2(3H)-Furanone, 4,5-dihydro-4-acetyl-5-(p-chlorophenyl)-, (E)-, RefChem:1070215
| Molecular Formula | C12H11ClO3 |
|---|---|
| Molecular Weight | 238.04 g/mol |
| LogP | 2.5332 |
| Topological Polar Surface Area | 43.37 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 238.03967 |
| Heavy Atoms | 16 |
| Complexity | 424.39493 |
Chemical Identifiers
| CAS Number | 83144-11-0 |
|---|---|
| SMILES | CC(=O)C1CC(=O)OC1C2=CC=C(C=C2)Cl |
Product Overview
4-Acetyl-5-(4-chlorophenyl)oxolan-2-one (CAS 83144-11-0), with molecular formula C12H11ClO3 and molecular weight 238.04 g/mol. IUPAC: 4-acetyl-5-(4-chlorophenyl)oxolan-2-one.
Chemical Property Profile of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one
Property Insights of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one
The XLogP value of 2.5332 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one. With a topological polar surface area (TPSA) of 43.37 Ų, 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one?
The CAS number of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one is 83144-11-0.
What is the molecular formula of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one?
The molecular formula of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one is C12H11ClO3.
What is the molecular weight of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one?
The molecular weight of 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one is 238.04 g/mol.
Where can I buy 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one?
You can request a quote for 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-Acetyl-5-(4-chlorophenyl)oxolan-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.