![(4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone structure](/static/products/831/831185-46-7.png)
(4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone
TL;DR: (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone (CAS 831185-46-7) is a chemical compound with molecular formula C21H20F3N5O3S and molecular weight 479.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
furan-2-yl-[4-[5-thiophen-2-yl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl]methanone
Also Known As: (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone, furan-2-yl(4-{[5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}piperazin-1-yl)methanone, 3-{[4-(2-furoyl)-1-piperazinyl]carbonyl}-5-(2-thienyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine, 4-(2-furylcarbonyl)piperazinyl 5-(2-thienyl)-7-(trifluoromethyl)(4H,5H,6H,7H-p yrazolo[1,5-a]1,3-diazaperhydroin-3-yl) ketone, furan-2-yl-[4-[5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl]methanone
| Molecular Formula | C21H20F3N5O3S |
|---|---|
| Molecular Weight | 479.12 g/mol |
| LogP | 3.7961 |
| Topological Polar Surface Area | 83.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 479.1239 |
| Heavy Atoms | 33 |
| Complexity | 1134.784 |
Chemical Identifiers
| CAS Number | 831185-46-7 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC=CO2)C(=O)C3=C4NC(CC(N4N=C3)C(F)(F)F)C5=CC=CS5 |
Product Overview
(4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone (CAS 831185-46-7), with molecular formula C21H20F3N5O3S and molecular weight 479.12 g/mol. IUPAC: furan-2-yl-[4-[5-thiophen-2-yl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl]methanone.
Chemical Property Profile of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone
Property Insights of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone
The XLogP value of 3.7961 indicates that (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.61 Ų falls within the moderate polarity range, balancing permeability and solubility for (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone. Following Lipinski's Rule of Five, (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone?
The CAS number of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone is 831185-46-7.
What is the molecular formula of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone?
The molecular formula of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone is C21H20F3N5O3S.
What is the molecular weight of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone?
The molecular weight of (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone is 479.12 g/mol.
Where can I buy (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone?
You can request a quote for (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (4-(furan-2-carbonyl)piperazin-1-yl)(5-(thiophen-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.