![N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide structure](/static/products/828/828286-33-5.png)
N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide
TL;DR: N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide (CAS 828286-33-5) is a chemical compound with molecular formula C19H17F2N3O3S2 and molecular weight 437.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide
Also Known As: N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide, N-[4-(difluoromethoxy)-3-ethoxy-phenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanyl-acetamide, N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-{[4-(thiophen-2-yl)pyrimidin-2-yl]sulfanyl}acetamide, N~1~-[4-(DIFLUOROMETHOXY)-3-ETHOXYPHENYL]-2-{[4-(2-THIENYL)-2-PYRIMIDINYL]SULFANYL}ACETAMIDE
| Molecular Formula | C19H17F2N3O3S2 |
|---|---|
| Molecular Weight | 437.07 g/mol |
| LogP | 4.936 |
| Topological Polar Surface Area | 73.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 437.06793 |
| Heavy Atoms | 29 |
| Complexity | 955.63226 |
Chemical Identifiers
| CAS Number | 828286-33-5 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)NC(=O)CSC2=NC=CC(=N2)C3=CC=CS3)OC(F)F |
Product Overview
N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide (CAS 828286-33-5), with molecular formula C19H17F2N3O3S2 and molecular weight 437.07 g/mol. IUPAC: N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide.
Chemical Property Profile of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide
Property Insights of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide
The XLogP value of 4.936 indicates that N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.34 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide. Following Lipinski's Rule of Five, N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide?
The CAS number of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide is 828286-33-5.
What is the molecular formula of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide?
The molecular formula of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide is C19H17F2N3O3S2.
What is the molecular weight of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide?
The molecular weight of N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide is 437.07 g/mol.
Where can I buy N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide?
You can request a quote for N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-[4-(difluoromethoxy)-3-ethoxyphenyl]-2-(4-thiophen-2-ylpyrimidin-2-yl)sulfanylacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.