![6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile structure](/static/products/828/828280-25-7.png)
6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile
TL;DR: 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile (CAS 828280-25-7) is a chemical compound with molecular formula C24H16F2N4O3 and molecular weight 446.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-amino-4-[4-(difluoromethoxy)phenyl]-3-(furan-2-yl)-1-phenyl-4H-pyrano[3,2-d]pyrazole-5-carbonitrile
Also Known As: 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-[4-(difluoromethoxy)phenyl]-3-(furan-2-yl)-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-[4-(difluoromethoxy)phenyl]-3-(furan-2-yl)-1-phenyl-4H-pyrano[2,3-c]pyrazole-5-carbonitrile, 6-AMINO-4-[4-(DIFLUOROMETHOXY)PHENYL]-3-(2-FURYL)-1-PHENYL-1,4-DIHYDROPYRANO[2,3-C]PYRAZOL-5-YL CYANIDE, 6-amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furyl)-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
| Molecular Formula | C24H16F2N4O3 |
|---|---|
| Molecular Weight | 446.12 g/mol |
| LogP | 4.95188 |
| Topological Polar Surface Area | 99.23 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 446.11905 |
| Heavy Atoms | 33 |
| Complexity | 1355.4677 |
Chemical Identifiers
| CAS Number | 828280-25-7 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C3=C(C(C(=C(O3)N)C#N)C4=CC=C(C=C4)OC(F)F)C(=N2)C5=CC=CO5 |
Product Overview
6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile (CAS 828280-25-7), with molecular formula C24H16F2N4O3 and molecular weight 446.12 g/mol. IUPAC: 6-amino-4-[4-(difluoromethoxy)phenyl]-3-(furan-2-yl)-1-phenyl-4H-pyrano[3,2-d]pyrazole-5-carbonitrile.
Chemical Property Profile of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile
Property Insights of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile
The XLogP value of 4.95188 indicates that 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.23 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile. Following Lipinski's Rule of Five, 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile?
The CAS number of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile is 828280-25-7.
What is the molecular formula of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile?
The molecular formula of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile is C24H16F2N4O3.
What is the molecular weight of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile?
The molecular weight of 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile is 446.12 g/mol.
Where can I buy 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile?
You can request a quote for 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 6-Amino-4-[4-(difluoromethoxy)phenyl]-3-(2-furanyl)-1,4-dihydro-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.