2,4-Diamino-6-chloromethylpteridine hydrochloride structure

2,4-Diamino-6-chloromethylpteridine hydrochloride

TL;DR: 2,4-Diamino-6-chloromethylpteridine hydrochloride (CAS 82778-08-3) is a chemical compound with molecular formula C7H8Cl2N6 and molecular weight 246.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-(chloromethyl)pteridine-2,4-diamine;hydrochloride

Also Known As: Methotrexate Impurity 21, 2,4-Dcmpt, 6-(Chloromethyl)pteridine-2,4-diamine monohydrochloride, Methotrexate Impurity 32, 6-(chloromethyl)pteridine-2,4-diamine hydrochloride

CAS: 82778-08-3
Molecular Formula C7H8Cl2N6
Molecular Weight 246.02 g/mol
LogP 0.7448
Topological Polar Surface Area 104.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 246.01875
Heavy Atoms 15
Complexity 203.0

Chemical Identifiers

CAS Number 82778-08-3
SMILES C1=C(N=C2C(=NC(=NC2=N1)N)N)CCl.Cl
InChIKey SDZKFWPFFHILFI-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (9 patents) Pharmaceutical Intermediates (9 patents)

Product Overview

2,4-Diamino-6-chloromethylpteridine hydrochloride (CAS 82778-08-3), with molecular formula C7H8Cl2N6 and molecular weight 246.02 g/mol. IUPAC: 6-(chloromethyl)pteridine-2,4-diamine;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2,4-Diamino-6-chloromethylpteridine hydrochloride

XLogP
0.7448
TPSA (Topological Polar Surface Area)
104.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
15
Complexity
203.0
Exact Mass
246.01875
Monoisotopic Mass
246.01875
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2,4-Diamino-6-chloromethylpteridine hydrochloride

The XLogP value of 0.7448 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,4-Diamino-6-chloromethylpteridine hydrochloride. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2,4-Diamino-6-chloromethylpteridine hydrochloride. Following Lipinski's Rule of Five, 2,4-Diamino-6-chloromethylpteridine hydrochloride has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2,4-Diamino-6-chloromethylpteridine hydrochloride?

The CAS number of 2,4-Diamino-6-chloromethylpteridine hydrochloride is 82778-08-3.

What is the molecular formula of 2,4-Diamino-6-chloromethylpteridine hydrochloride?

The molecular formula of 2,4-Diamino-6-chloromethylpteridine hydrochloride is C7H8Cl2N6.

What is the molecular weight of 2,4-Diamino-6-chloromethylpteridine hydrochloride?

The molecular weight of 2,4-Diamino-6-chloromethylpteridine hydrochloride is 246.02 g/mol.

Where can I buy 2,4-Diamino-6-chloromethylpteridine hydrochloride?

You can request a quote for 2,4-Diamino-6-chloromethylpteridine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2,4-Diamino-6-chloromethylpteridine hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for 2,4-Diamino-6-chloromethylpteridine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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