![5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine structure](/static/products/827/827586-41-4.png)
5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine
TL;DR: 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 827586-41-4) is a chemical compound with molecular formula C8H5F4N3 and molecular weight 219.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine
Also Known As: 5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine, 5,7-Bis(difluoromethyl)pyrazolo1,5-apyrimidine, pyrazolo[1,5-a]pyrimidine, 5,7-bis(difluoromethyl)-, 5,7-bis(difluoromethyl)-8-hydropyrazolo[1,5-a]pyrimidine, 2,4-bis(difluoromethyl)-1,5,9-triazabicyclo[4.3.0]nona-2,4,6,8-tetraene
| Molecular Formula | C8H5F4N3 |
|---|---|
| Molecular Weight | 219.04 g/mol |
| LogP | 2.6045 |
| Topological Polar Surface Area | 30.19 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 219.04196 |
| Heavy Atoms | 15 |
| Complexity | 479.69156 |
Chemical Identifiers
| CAS Number | 827586-41-4 |
|---|---|
| SMILES | C1=C2N=C(C=C(N2N=C1)C(F)F)C(F)F |
Product Overview
5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 827586-41-4), with molecular formula C8H5F4N3 and molecular weight 219.04 g/mol. IUPAC: 5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine.
Chemical Property Profile of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine
Property Insights of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine
The XLogP value of 2.6045 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine. With a topological polar surface area (TPSA) of 30.19 Ų, 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine?
The CAS number of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine is 827586-41-4.
What is the molecular formula of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine?
The molecular formula of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine is C8H5F4N3.
What is the molecular weight of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine?
The molecular weight of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine is 219.04 g/mol.
Where can I buy 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine?
You can request a quote for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.