![4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one structure](/static/products/824/82475-71-6.png)
4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one
TL;DR: 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one (CAS 82475-71-6) is a chemical compound with molecular formula C14H23FN2O3Si and molecular weight 314.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one
Also Known As: 4-[tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyr, 4-[tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one, 4-{[tert-Butyldi(methyl)silyl]oxy}-5-fluoro-1-(oxolan-2-yl)pyrimidin-2(1H)-one
| Molecular Formula | C14H23FN2O3Si |
|---|---|
| Molecular Weight | 314.15 g/mol |
| LogP | 3.0754 |
| Topological Polar Surface Area | 51.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 314.1462 |
| Heavy Atoms | 21 |
| Complexity | 497.0 |
Chemical Identifiers
| CAS Number | 82475-71-6 |
|---|---|
| SMILES | CC(C)(C)[Si](C)(C)OC1=NC(=O)N(C=C1F)C2CCCO2 |
| InChIKey | BQDQNAYCXAFZQN-UHFFFAOYSA-N |
Product Overview
4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one (CAS 82475-71-6), with molecular formula C14H23FN2O3Si and molecular weight 314.15 g/mol. IUPAC: 4-[tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one.
Chemical Property Profile of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one
Property Insights of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one
The XLogP value of 3.0754 indicates that 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.1 Ų, 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one?
The CAS number of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one is 82475-71-6.
What is the molecular formula of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one?
The molecular formula of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one is C14H23FN2O3Si.
What is the molecular weight of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one?
The molecular weight of 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one is 314.15 g/mol.
Where can I buy 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one?
You can request a quote for 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-[Tert-butyl(dimethyl)silyl]oxy-5-fluoro-1-(oxolan-2-yl)pyrimidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.