5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine
TL;DR: 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine (CAS 82475-70-5) is a chemical compound with molecular formula C16H31FN2O2Si2 and molecular weight 358.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
tert-butyl-[2-[tert-butyl(dimethyl)silyl]oxy-5-fluoropyrimidin-4-yl]oxy-dimethylsilane
Also Known As: 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine, 2,4-Bis{[tert-butyldi(methyl)silyl]oxy}-5-fluoropyrimidine, tert-butyl-[2-[tert-butyl(dimethyl)silyl]oxy-5-fluoropyrimidin-4-yl]oxy-dimethylsilane, tert-butyl-[2-[tert-butyl(dimethyl)silyl]oxy-5-fluoropyrimid, 2,4-BIS[(TERT-BUTYLDIMETHYLSILYL)OXY]-5-FLUOROPYRIMIDINE
| Molecular Formula | C16H31FN2O2Si2 |
|---|---|
| Molecular Weight | 358.19 g/mol |
| LogP | 5.3837 |
| Topological Polar Surface Area | 44.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 358.1908 |
| Heavy Atoms | 23 |
| Complexity | 406.0 |
Chemical Identifiers
| CAS Number | 82475-70-5 |
|---|---|
| SMILES | CC(C)(C)[Si](C)(C)OC1=NC(=NC=C1F)O[Si](C)(C)C(C)(C)C |
| InChIKey | SUKJMFHDLPIHPZ-UHFFFAOYSA-N |
Product Overview
5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine (CAS 82475-70-5), with molecular formula C16H31FN2O2Si2 and molecular weight 358.19 g/mol. IUPAC: tert-butyl-[2-[tert-butyl(dimethyl)silyl]oxy-5-fluoropyrimidin-4-yl]oxy-dimethylsilane.
Chemical Property Profile of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine
Property Insights of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine
The XLogP value of 5.3837 indicates that 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.2 Ų, 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine?
The CAS number of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine is 82475-70-5.
What is the molecular formula of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine?
The molecular formula of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine is C16H31FN2O2Si2.
What is the molecular weight of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine?
The molecular weight of 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine is 358.19 g/mol.
Where can I buy 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine?
You can request a quote for 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluoro-2,4-bis(tert-butyldimethylsilyloxy)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.