5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine
TL;DR: 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine (CAS 82473-10-7) is a chemical compound with molecular formula C11H11ClF2N2O5 and molecular weight 324.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[(E)-2-chloro-1,2-difluoroethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine, 5-((E)-2-Chloro-1,2-difluoro-vinyl)-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione, 5-[(E)-2-chloro-1,2-difluoro-vinyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, 5-[(E)-2-chloro-1,2-difluoroethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
| Molecular Formula | C11H11ClF2N2O5 |
|---|---|
| Molecular Weight | 324.03 g/mol |
| LogP | -0.0188 |
| Topological Polar Surface Area | 104.55 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 324.03247 |
| Heavy Atoms | 21 |
| Complexity | 681.9265 |
Chemical Identifiers
| CAS Number | 82473-10-7 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)/C(=C(/F)\Cl)/F)CO)O |
Product Overview
5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine (CAS 82473-10-7), with molecular formula C11H11ClF2N2O5 and molecular weight 324.03 g/mol. IUPAC: 5-[(E)-2-chloro-1,2-difluoroethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine
Property Insights of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine
The XLogP value of -0.0188 indicates that 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.55 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine. Following Lipinski's Rule of Five, 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine?
The CAS number of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine is 82473-10-7.
What is the molecular formula of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine?
The molecular formula of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine is C11H11ClF2N2O5.
What is the molecular weight of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine?
The molecular weight of 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine is 324.03 g/mol.
Where can I buy 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine?
You can request a quote for 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine?
Yes, KEHONG BIO provides custom synthesis services for 5-(2-Chloro-1,2-difluoroethenyl)-2'-deoxy-(E)uridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.