4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one
TL;DR: 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one (CAS 82447-76-5) is a chemical compound with molecular formula C18H12N2OS and molecular weight 304.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4,6-diphenyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Also Known As: 4,6-Diphenylisothiazolo[5,4-b]pyridin-3(2H)-one, 4,6-diphenyl-[1,2]thiazolo[5,4-b]pyridin-3-one, 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one, 4,6-Diphenyl[1,2]thiazolo[5,4-b]pyridin-3(2H)-one, 3-oxo-4,6-diphenyl-2,3-dihydroisothiazolo[5,4-b]pyridine
| Molecular Formula | C18H12N2OS |
|---|---|
| Molecular Weight | 304.07 g/mol |
| LogP | 4.3186 |
| Topological Polar Surface Area | 45.75 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 304.06705 |
| Heavy Atoms | 22 |
| Complexity | 987.9639 |
Chemical Identifiers
| CAS Number | 82447-76-5 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=CC(=NC3=C2C(=O)NS3)C4=CC=CC=C4 |
Product Overview
4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one (CAS 82447-76-5), with molecular formula C18H12N2OS and molecular weight 304.07 g/mol. IUPAC: 4,6-diphenyl-[1,2]thiazolo[5,4-b]pyridin-3-one.
Chemical Property Profile of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one
Property Insights of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one
The XLogP value of 4.3186 indicates that 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.75 Ų, 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one?
The CAS number of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one is 82447-76-5.
What is the molecular formula of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one?
The molecular formula of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one is C18H12N2OS.
What is the molecular weight of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one?
The molecular weight of 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one is 304.07 g/mol.
Where can I buy 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one?
You can request a quote for 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4,6-Diphenylisothiazolo(5,4-b)pyridin-3(2H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.