N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine structure

N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine

TL;DR: N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine (CAS 82205-20-7) is a chemical compound with molecular formula C21H27N5O6 and molecular weight 445.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[(2S)-2-[[2-[(4-hydroxybenzoyl)amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid

Also Known As: Ohip-his-leu, P-HYDROXYHIPPURYL-HIS-LEU-OH, P-hydroxyhippuryl-his-leu, p-Hydroxyhippuryl-HL-OH, 4-Hydroxyhippuryl-histidyl-leucine

CAS: 82205-20-7
Molecular Formula C21H27N5O6
Molecular Weight 445.20 g/mol
LogP 1.0
Topological Polar Surface Area 174.0 Ų
Hydrogen Bond Donors 6
Hydrogen Bond Acceptors 7
Rotatable Bonds 11
Exact Mass 445.19614
Heavy Atoms 32
Complexity 665.0

Chemical Identifiers

CAS Number 82205-20-7
SMILES CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CN=CN1)NC(=O)CNC(=O)C2=CC=C(C=C2)O
InChIKey IHVRJTCVMKJNRP-IRXDYDNUSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Biotechnology (6 patents) Food Additives (2 patents) Peptides & Amino Acids (2 patents) Pharmaceutical Intermediates (4 patents)

Product Overview

N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine (CAS 82205-20-7), with molecular formula C21H27N5O6 and molecular weight 445.20 g/mol. IUPAC: (2S)-2-[[(2S)-2-[[2-[(4-hydroxybenzoyl)amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine

XLogP
1.0
TPSA (Topological Polar Surface Area)
174.0
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
7
Rotatable Bonds
11
Heavy Atoms
32
Complexity
665.0
Exact Mass
445.19614
Monoisotopic Mass
445.19614
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine

The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine. The TPSA of 174.0 Ų indicates high polarity, suggesting N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine has 6 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine?

The CAS number of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine is 82205-20-7.

What is the molecular formula of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine?

The molecular formula of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine is C21H27N5O6.

What is the molecular weight of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine?

The molecular weight of N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine is 445.20 g/mol.

Where can I buy N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine?

You can request a quote for N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine?

Yes, KEHONG BIO provides custom synthesis services for N-(4-Hydroxybenzoyl)glycyl-L-histidyl-L-leucine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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