Etolotifen structure

Etolotifen

TL;DR: Etolotifen (CAS 82140-22-5) is a chemical compound with molecular formula C24H29NO4S and molecular weight 427.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[1-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]piperidin-4-ylidene]-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one

Also Known As: Etolotifen, etolotifene, etolotifeno, Etolotifen [INN], etolotifenum

CAS: 82140-22-5
Molecular Formula C24H29NO4S
Molecular Weight 427.18 g/mol
LogP 2.3
Topological Polar Surface Area 87.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 8
Exact Mass 427.18173
Heavy Atoms 30
Complexity 600.0

Chemical Identifiers

CAS Number 82140-22-5
SMILES C1CN(CCC1=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CCOCCOCCO
InChIKey BPEQXNIRIPLFRW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Biotechnology (1 patents) Heterocyclic Building Blocks (44 patents) Organic Building Blocks (1 patents) Peptides & Amino Acids (1 patents) Pharmaceutical Intermediates (75 patents)

Product Overview

Etolotifen (CAS 82140-22-5), with molecular formula C24H29NO4S and molecular weight 427.18 g/mol. IUPAC: 2-[1-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]piperidin-4-ylidene]-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Etolotifen

XLogP
2.3
TPSA (Topological Polar Surface Area)
87.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
8
Heavy Atoms
30
Complexity
600.0
Exact Mass
427.18173
Monoisotopic Mass
427.18173
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Etolotifen

The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Etolotifen. The TPSA of 87.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Etolotifen. Following Lipinski's Rule of Five, Etolotifen has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Etolotifen?

The CAS number of Etolotifen is 82140-22-5.

What is the molecular formula of Etolotifen?

The molecular formula of Etolotifen is C24H29NO4S.

What is the molecular weight of Etolotifen?

The molecular weight of Etolotifen is 427.18 g/mol.

Where can I buy Etolotifen?

You can request a quote for Etolotifen directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Etolotifen?

Yes, KEHONG BIO provides custom synthesis services for Etolotifen and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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