Dexamethasone-17-carboxamide
TL;DR: Dexamethasone-17-carboxamide (CAS 82137-90-4) is a chemical compound with molecular formula C21H28FNO4 and molecular weight 377.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxamide
Also Known As: Dexamethasone-17-carboxamide, DX-17-Carboxamide, OXDEX, 17-Dxb, 17-Carboxamide dexamethasone
| Molecular Formula | C21H28FNO4 |
|---|---|
| Molecular Weight | 377.20 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 377.20023 |
| Heavy Atoms | 27 |
| Complexity | 793.0 |
Chemical Identifiers
| CAS Number | 82137-90-4 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)N)O)C)O)F)C |
| InChIKey | PILCISDJZUQFIS-AFKBWYBQSA-N |
Product Overview
Dexamethasone-17-carboxamide (CAS 82137-90-4), with molecular formula C21H28FNO4 and molecular weight 377.20 g/mol. IUPAC: (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxamide.
Chemical Property Profile of Dexamethasone-17-carboxamide
Property Insights of Dexamethasone-17-carboxamide
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dexamethasone-17-carboxamide. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Dexamethasone-17-carboxamide. Following Lipinski's Rule of Five, Dexamethasone-17-carboxamide has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dexamethasone-17-carboxamide?
The CAS number of Dexamethasone-17-carboxamide is 82137-90-4.
What is the molecular formula of Dexamethasone-17-carboxamide?
The molecular formula of Dexamethasone-17-carboxamide is C21H28FNO4.
What is the molecular weight of Dexamethasone-17-carboxamide?
The molecular weight of Dexamethasone-17-carboxamide is 377.20 g/mol.
Where can I buy Dexamethasone-17-carboxamide?
You can request a quote for Dexamethasone-17-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dexamethasone-17-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for Dexamethasone-17-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.