D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr structure

D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr

TL;DR: D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr (CAS 82131-82-6) is a chemical compound with molecular formula C52H74N12O9 and molecular weight 1010.57 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[2-[[2-[[2-[[2-[[2-[[1-[2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

Also Known As: H 77, D-HIS-PRO-PHE-HIS-LEU-PSI-(CH2NH)-*LEU-V AL-TYR, ((S)-2-((S)-2-((S)-2-((S)-1-(D-histidyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-(1H-imidazol-4-yl)propanamido)-4-methylpentyl)-L-leucyl-L-valyl-L-tyrosine, 2-[[2-[[2-[[2-[[2-[[2-[[1-[2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

CAS: 82131-82-6
Molecular Formula C52H74N12O9
Molecular Weight 1010.57 g/mol
LogP 1.6423
Topological Polar Surface Area 318.75 Ų
Hydrogen Bond Donors 11
Hydrogen Bond Acceptors 12
Rotatable Bonds 28
Exact Mass 1010.5702
Heavy Atoms 73
Complexity 2398.1184

Chemical Identifiers

CAS Number 82131-82-6
SMILES CC(C)CC(CNC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)C(CC2=CN=CN2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCN4C(=O)C(CC5=CN=CN5)N

Product Overview

D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr (CAS 82131-82-6), with molecular formula C52H74N12O9 and molecular weight 1010.57 g/mol. IUPAC: 2-[[2-[[2-[[2-[[2-[[2-[[1-[2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr

XLogP
1.6423
TPSA (Topological Polar Surface Area)
318.75
Hydrogen Bond Donors
11
Hydrogen Bond Acceptors
12
Rotatable Bonds
28
Heavy Atoms
73
Complexity
2398.1184
Exact Mass
1010.5702
Monoisotopic Mass
1010.5702
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr

The XLogP value of 1.6423 suggests moderate lipophilicity, balancing water solubility and membrane permeability for D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr. The TPSA of 318.75 Ų indicates high polarity, suggesting D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr has 11 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr?

The CAS number of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr is 82131-82-6.

What is the molecular formula of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr?

The molecular formula of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr is C52H74N12O9.

What is the molecular weight of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr?

The molecular weight of D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr is 1010.57 g/mol.

Where can I buy D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr?

You can request a quote for D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr?

Yes, KEHONG BIO provides custom synthesis services for D-His-pro-phe-his-leu-psi-(CH2NH)-*leu-V AL-tyr and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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