Amflutizole
TL;DR: Amflutizole (CAS 82114-19-0) is a chemical compound with molecular formula C11H7F3N2O2S and molecular weight 288.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid
Also Known As: AMFLUTIZOLE, Amflutizol, Amflutizolum, Amflutizol [Spanish], Amflutizolum [Latin]
| Molecular Formula | C11H7F3N2O2S |
|---|---|
| Molecular Weight | 288.02 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 104.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 288.01804 |
| Heavy Atoms | 19 |
| Complexity | 353.0 |
Chemical Identifiers
| CAS Number | 82114-19-0 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)C2=NSC(=C2N)C(=O)O |
| InChIKey | KVMCEGAWQYTFKC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Amflutizole (CAS 82114-19-0), with molecular formula C11H7F3N2O2S and molecular weight 288.02 g/mol. IUPAC: 4-amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid.
Chemical Property Profile of Amflutizole
Property Insights of Amflutizole
The XLogP value of 3.3 indicates that Amflutizole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Amflutizole. Following Lipinski's Rule of Five, Amflutizole has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amflutizole?
The CAS number of Amflutizole is 82114-19-0.
What is the molecular formula of Amflutizole?
The molecular formula of Amflutizole is C11H7F3N2O2S.
What is the molecular weight of Amflutizole?
The molecular weight of Amflutizole is 288.02 g/mol.
Where can I buy Amflutizole?
You can request a quote for Amflutizole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amflutizole?
Yes, KEHONG BIO provides custom synthesis services for Amflutizole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.