Lotemax
TL;DR: Lotemax (CAS 82034-46-6) is a chemical compound with molecular formula C24H31ClO7 and molecular weight 466.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
chloromethyl (10R,11S,13S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
Also Known As: Lotemax, Alrex, Loteflam, Zylet, Loteprednol etabonate
| Molecular Formula | C24H31ClO7 |
|---|---|
| Molecular Weight | 466.18 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 99.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 466.17584 |
| Heavy Atoms | 32 |
| Complexity | 882.0 |
Chemical Identifiers
| CAS Number | 82034-46-6 |
|---|---|
| SMILES | CCOC(=O)O[C@@]1(CCC2[C@@]1(C[C@@H](C3C2CCC4=CC(=O)C=C[C@]34C)O)C)C(=O)OCCl |
| InChIKey | DMKSVUSAATWOCU-OEWWVBLQSA-N |
Product Overview
Lotemax (CAS 82034-46-6), with molecular formula C24H31ClO7 and molecular weight 466.18 g/mol. IUPAC: chloromethyl (10R,11S,13S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate.
Chemical Property Profile of Lotemax
Property Insights of Lotemax
The XLogP value of 3.9 indicates that Lotemax is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Lotemax. Following Lipinski's Rule of Five, Lotemax has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lotemax?
The CAS number of Lotemax is 82034-46-6.
What is the molecular formula of Lotemax?
The molecular formula of Lotemax is C24H31ClO7.
What is the molecular weight of Lotemax?
The molecular weight of Lotemax is 466.18 g/mol.
Where can I buy Lotemax?
You can request a quote for Lotemax directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lotemax?
Yes, KEHONG BIO provides custom synthesis services for Lotemax and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.