Leu-Enkephalin structure

Leu-Enkephalin

TL;DR: Leu-Enkephalin (CAS 81678-16-2) is a chemical compound with molecular formula C28H37N5O7 and molecular weight 555.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid

Also Known As: Leu-enkephalin, [Leu5]-Enkephalin, leucine enkephalin, Enkephalin, Enkephalins

CAS: 81678-16-2
Molecular Formula C28H37N5O7
Molecular Weight 555.27 g/mol
LogP -2.3
Topological Polar Surface Area 200.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 8
Rotatable Bonds 15
Exact Mass 555.2693
Heavy Atoms 40
Complexity 854.0

Chemical Identifiers

CAS Number 81678-16-2
SMILES CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)N
InChIKey URLZCHNOLZSCCA-VABKMULXSA-N

Patent-Derived Application Labels

Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (3 patents) Biotechnology (22 patents) Heterocyclic Building Blocks (6 patents) Organic Building Blocks (4 patents) Organometallic Reagents (1 patents) +2 more

Product Overview

Leu-Enkephalin (CAS 81678-16-2), with molecular formula C28H37N5O7 and molecular weight 555.27 g/mol. IUPAC: (2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Leu-Enkephalin

XLogP
-2.3
TPSA (Topological Polar Surface Area)
200.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
8
Rotatable Bonds
15
Heavy Atoms
40
Complexity
854.0
Exact Mass
555.2693
Monoisotopic Mass
555.2693
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Leu-Enkephalin

The XLogP value of -2.3 indicates that Leu-Enkephalin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 200.0 Ų indicates high polarity, suggesting Leu-Enkephalin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Leu-Enkephalin has 7 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Leu-Enkephalin?

The CAS number of Leu-Enkephalin is 81678-16-2.

What is the molecular formula of Leu-Enkephalin?

The molecular formula of Leu-Enkephalin is C28H37N5O7.

What is the molecular weight of Leu-Enkephalin?

The molecular weight of Leu-Enkephalin is 555.27 g/mol.

Where can I buy Leu-Enkephalin?

You can request a quote for Leu-Enkephalin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Leu-Enkephalin?

Yes, KEHONG BIO provides custom synthesis services for Leu-Enkephalin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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