Levlofexidine structure

Levlofexidine

TL;DR: Levlofexidine (CAS 81447-79-2) is a chemical compound with molecular formula C11H12Cl2N2O and molecular weight 258.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[(1R)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole

Also Known As: Levlofexidine, (R)-Lofexidine, Lofexidine, levlofexidina, levlofexidinum

CAS: 81447-79-2
Molecular Formula C11H12Cl2N2O
Molecular Weight 258.03 g/mol
LogP 2.7624
Topological Polar Surface Area 33.62 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 3
Exact Mass 258.03265
Heavy Atoms 16
Complexity 400.19562

Chemical Identifiers

CAS Number 81447-79-2
SMILES C[C@H](C1=NCCN1)OC2=C(C=CC=C2Cl)Cl

Product Overview

Levlofexidine (CAS 81447-79-2), with molecular formula C11H12Cl2N2O and molecular weight 258.03 g/mol. IUPAC: 2-[(1R)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Levlofexidine

XLogP
2.7624
TPSA (Topological Polar Surface Area)
33.62
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
3
Heavy Atoms
16
Complexity
400.19562
Exact Mass
258.03265
Monoisotopic Mass
258.03265
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Levlofexidine

The XLogP value of 2.7624 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Levlofexidine. With a topological polar surface area (TPSA) of 33.62 Ų, Levlofexidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Levlofexidine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Levlofexidine?

The CAS number of Levlofexidine is 81447-79-2.

What is the molecular formula of Levlofexidine?

The molecular formula of Levlofexidine is C11H12Cl2N2O.

What is the molecular weight of Levlofexidine?

The molecular weight of Levlofexidine is 258.03 g/mol.

Where can I buy Levlofexidine?

You can request a quote for Levlofexidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Levlofexidine?

Yes, KEHONG BIO provides custom synthesis services for Levlofexidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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