Losulazine Hydrochloride
TL;DR: Losulazine Hydrochloride (CAS 81435-67-8) is a chemical compound with molecular formula C27H23ClF4N4O3S and molecular weight 594.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone;hydrochloride
Also Known As: Losulazine hydrochloride, Losulazine HCl, Losulazine, Losulazine monohydrochloride, Losulazine hydrochloride [USAN]
| Molecular Formula | C27H23ClF4N4O3S |
|---|---|
| Molecular Weight | 594.11 g/mol |
| LogP | 5.7 |
| Topological Polar Surface Area | 91.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 5 |
| Exact Mass | 594.1116 |
| Heavy Atoms | 40 |
| Complexity | 938.0 |
Chemical Identifiers
| CAS Number | 81435-67-8 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC=C(C=C2)NC3=C4C=CC(=CC4=NC=C3)C(F)(F)F)S(=O)(=O)C5=CC=C(C=C5)F.Cl |
| InChIKey | MGOGSSZOPFFXLA-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Losulazine Hydrochloride (CAS 81435-67-8), with molecular formula C27H23ClF4N4O3S and molecular weight 594.11 g/mol. IUPAC: [4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone;hydrochloride.
Chemical Property Profile of Losulazine Hydrochloride
Property Insights of Losulazine Hydrochloride
The XLogP value of 5.7 indicates that Losulazine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Losulazine Hydrochloride. Following Lipinski's Rule of Five, Losulazine Hydrochloride has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losulazine Hydrochloride?
The CAS number of Losulazine Hydrochloride is 81435-67-8.
What is the molecular formula of Losulazine Hydrochloride?
The molecular formula of Losulazine Hydrochloride is C27H23ClF4N4O3S.
What is the molecular weight of Losulazine Hydrochloride?
The molecular weight of Losulazine Hydrochloride is 594.11 g/mol.
Where can I buy Losulazine Hydrochloride?
You can request a quote for Losulazine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losulazine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Losulazine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.