8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline
TL;DR: 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline (CAS 81358-69-2) is a chemical compound with molecular formula C12H11F3N2O2 and molecular weight 272.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-methoxy-5-(2,2,2-trifluoroethoxy)quinolin-8-amine
Also Known As: 8-amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline, 6-Methoxy-5-(2,2,2-trifluoroethoxy)-8-quinolinamine, 6-methoxy-5-(2,2,2-trifluoroethoxy)quinolin-8-amine, 6-Methoxy-5-(2,2,2-trifluoroethoxy)-8-quinolinamine #, 8-Amino-6-methoxy-5-[2,2,2-trifluoroethoxy]quinoline
| Molecular Formula | C12H11F3N2O2 |
|---|---|
| Molecular Weight | 272.08 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 57.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 272.07727 |
| Heavy Atoms | 19 |
| Complexity | 301.0 |
Chemical Identifiers
| CAS Number | 81358-69-2 |
|---|---|
| SMILES | COC1=C(C2=C(C(=C1)N)N=CC=C2)OCC(F)(F)F |
| InChIKey | XRYWVRJPNLNRLI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline (CAS 81358-69-2), with molecular formula C12H11F3N2O2 and molecular weight 272.08 g/mol. IUPAC: 6-methoxy-5-(2,2,2-trifluoroethoxy)quinolin-8-amine.
Chemical Property Profile of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline
Property Insights of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline. With a topological polar surface area (TPSA) of 57.4 Ų, 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline?
The CAS number of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline is 81358-69-2.
What is the molecular formula of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline?
The molecular formula of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline is C12H11F3N2O2.
What is the molecular weight of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline?
The molecular weight of 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline is 272.08 g/mol.
Where can I buy 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline?
You can request a quote for 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 8-Amino-6-methoxy-5-(2,2,2-trifluoroethoxy)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.