Phosphodifluoromethylphosphonic acid-adenylate ester structure

Phosphodifluoromethylphosphonic acid-adenylate ester

TL;DR: Phosphodifluoromethylphosphonic acid-adenylate ester (CAS 81336-78-9) is a chemical compound with molecular formula C11H16F2N5O12P3 and molecular weight 541.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]-difluoromethyl]phosphonic acid

Also Known As: phosphodifluoromethylphosphonic acid-adenylate ester, J1.089.470K, 5'-Adenylic acid, anhydride with P,P'-(difluoromethylene)bis[phosphonic acid], ATF, 5 -O-[[(Difluorophosphonomethyl)phosphonyloxy]phosphonyl]adenosine

CAS: 81336-78-9
Molecular Formula C11H16F2N5O12P3
Molecular Weight 541.00 g/mol
LogP -5.1
Topological Polar Surface Area 270.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 18
Rotatable Bonds 8
Exact Mass 540.9976
Heavy Atoms 33
Complexity 882.0

Chemical Identifiers

CAS Number 81336-78-9
SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(C(F)(F)P(=O)(O)O)O)O)O)N
InChIKey ODWAWOIUPXBZKQ-KQYNXXCUSA-N

Product Overview

Phosphodifluoromethylphosphonic acid-adenylate ester (CAS 81336-78-9), with molecular formula C11H16F2N5O12P3 and molecular weight 541.00 g/mol. IUPAC: [[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]-difluoromethyl]phosphonic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Phosphodifluoromethylphosphonic acid-adenylate ester

XLogP
-5.1
TPSA (Topological Polar Surface Area)
270.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
18
Rotatable Bonds
8
Heavy Atoms
33
Complexity
882.0
Exact Mass
540.9976
Monoisotopic Mass
540.9976
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Phosphodifluoromethylphosphonic acid-adenylate ester

The XLogP value of -5.1 indicates that Phosphodifluoromethylphosphonic acid-adenylate ester is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 270.0 Ų indicates high polarity, suggesting Phosphodifluoromethylphosphonic acid-adenylate ester may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Phosphodifluoromethylphosphonic acid-adenylate ester has 7 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Phosphodifluoromethylphosphonic acid-adenylate ester?

The CAS number of Phosphodifluoromethylphosphonic acid-adenylate ester is 81336-78-9.

What is the molecular formula of Phosphodifluoromethylphosphonic acid-adenylate ester?

The molecular formula of Phosphodifluoromethylphosphonic acid-adenylate ester is C11H16F2N5O12P3.

What is the molecular weight of Phosphodifluoromethylphosphonic acid-adenylate ester?

The molecular weight of Phosphodifluoromethylphosphonic acid-adenylate ester is 541.00 g/mol.

Where can I buy Phosphodifluoromethylphosphonic acid-adenylate ester?

You can request a quote for Phosphodifluoromethylphosphonic acid-adenylate ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Phosphodifluoromethylphosphonic acid-adenylate ester?

Yes, KEHONG BIO provides custom synthesis services for Phosphodifluoromethylphosphonic acid-adenylate ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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