克拉黴素
TL;DR: 克拉黴素 (CAS 81103-11-9) is a chemical compound with molecular formula C38H69NO13 and molecular weight 747.48 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
克拉黴素
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Also Known As: clarithromycin, Prevpac, Biaxin, Biaxin XL, 6-O-Methylerythromycin
| Molecular Formula | C38H69NO13 |
|---|---|
| Molecular Weight | 747.48 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 183.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 8 |
| Exact Mass | 747.47687 |
| Heavy Atoms | 52 |
| Complexity | 1190.0 |
Chemical Identifiers
| CAS Number | 81103-11-9 |
|---|---|
| SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O |
| InChIKey | AGOYDEPGAOXOCK-AVDMLEEESA-N |
Product Overview
克拉黴素 (CAS 81103-11-9), with molecular formula C38H69NO13 and molecular weight 747.48 g/mol. IUPAC: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione.
Chemical Property Profile of 克拉黴素
Property Insights of 克拉黴素
The XLogP value of 3.2 indicates that 克拉黴素 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 183.0 Ų indicates high polarity, suggesting 克拉黴素 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 克拉黴素 has 4 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 克拉黴素?
The CAS number of 克拉黴素 is 81103-11-9.
What is the molecular formula of 克拉黴素?
The molecular formula of 克拉黴素 is C38H69NO13.
What is the molecular weight of 克拉黴素?
The molecular weight of 克拉黴素 is 747.48 g/mol.
Where can I buy 克拉黴素?
You can request a quote for 克拉黴素 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 克拉黴素?
Yes, KEHONG BIO provides custom synthesis services for 克拉黴素 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.