RefChem:377776 structure

RefChem:377776

TL;DR: RefChem:377776 (CAS 80761-67-7) is a chemical compound with molecular formula C10H8N6O4 and molecular weight 276.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 2-cyano-2-(6,8-dioxo-5H-pyrimido[4,5-e][1,2,4]triazin-3-yl)acetate

Also Known As: Pyrimido(4,5-e)-as-triazine-3-acetic acid, 5,6,7,8-tetrahydro-alpha-cyano-6,8-dioxo-, ethyl ester, Ethyl cyano(6,8-dihydroxypyrimido[4,5-e][1,2,4]triazin-3-yl)acetate, ethyl 2-cyano-2-(6,8-dioxo-5H-pyrimido[4,5-e][1,2,4]triazin-3-yl)acetate, ethyl 2-cyano-2-{6,8-dioxo-5H,6H,7H,8H-pyrimido[4,5-e][1,2,4]triazin-3-yl}acetate, 5,6,7,8-Tetrahydro-alpha-cyano-6,8-dioxopyrimido[4,5-e]-1,2,4-triazine-3-acetic acid ethyl ester

CAS: 80761-67-7
Molecular Formula C10H8N6O4
Molecular Weight 276.06 g/mol
LogP -1.42832
Topological Polar Surface Area 154.48 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 8
Rotatable Bonds 3
Exact Mass 276.0607
Heavy Atoms 20
Complexity 816.83325

Chemical Identifiers

CAS Number 80761-67-7
SMILES CCOC(=O)C(C#N)C1=NC2=C(C(=O)NC(=O)N2)N=N1

Product Overview

RefChem:377776 (CAS 80761-67-7), with molecular formula C10H8N6O4 and molecular weight 276.06 g/mol. IUPAC: ethyl 2-cyano-2-(6,8-dioxo-5H-pyrimido[4,5-e][1,2,4]triazin-3-yl)acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:377776

XLogP
-1.42832
TPSA (Topological Polar Surface Area)
154.48
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
8
Rotatable Bonds
3
Heavy Atoms
20
Complexity
816.83325
Exact Mass
276.0607
Monoisotopic Mass
276.0607
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:377776

The XLogP value of -1.42832 indicates that RefChem:377776 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 154.48 Ų indicates high polarity, suggesting RefChem:377776 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, RefChem:377776 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:377776?

The CAS number of RefChem:377776 is 80761-67-7.

What is the molecular formula of RefChem:377776?

The molecular formula of RefChem:377776 is C10H8N6O4.

What is the molecular weight of RefChem:377776?

The molecular weight of RefChem:377776 is 276.06 g/mol.

Where can I buy RefChem:377776?

You can request a quote for RefChem:377776 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:377776?

Yes, KEHONG BIO provides custom synthesis services for RefChem:377776 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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