Clonidine and chlorthalidone structure

Clonidine and chlorthalidone

TL;DR: Clonidine and chlorthalidone (CAS 8067-84-3) is a chemical compound with molecular formula C23H20Cl3N5O4S and molecular weight 567.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide;N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine

Also Known As: Combipres, Combipresan, Combipresan 75, CLORPRES, Clonidine and chlorthalidone

CAS: 8067-84-3
Molecular Formula C23H20Cl3N5O4S
Molecular Weight 567.03 g/mol
LogP 3.2887
Topological Polar Surface Area 154.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 567.03015
Heavy Atoms 36
Complexity 786.0

Chemical Identifiers

CAS Number 8067-84-3
SMILES C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
InChIKey DLXKTNWIMHQWKG-UHFFFAOYSA-N

Product Overview

Clonidine and chlorthalidone (CAS 8067-84-3), with molecular formula C23H20Cl3N5O4S and molecular weight 567.03 g/mol. IUPAC: 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide;N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Clonidine and chlorthalidone

XLogP
3.2887
TPSA (Topological Polar Surface Area)
154.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
36
Complexity
786.0
Exact Mass
567.03015
Monoisotopic Mass
567.03015
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Clonidine and chlorthalidone

The XLogP value of 3.2887 indicates that Clonidine and chlorthalidone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 154.0 Ų indicates high polarity, suggesting Clonidine and chlorthalidone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Clonidine and chlorthalidone has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Clonidine and chlorthalidone?

The CAS number of Clonidine and chlorthalidone is 8067-84-3.

What is the molecular formula of Clonidine and chlorthalidone?

The molecular formula of Clonidine and chlorthalidone is C23H20Cl3N5O4S.

What is the molecular weight of Clonidine and chlorthalidone?

The molecular weight of Clonidine and chlorthalidone is 567.03 g/mol.

Where can I buy Clonidine and chlorthalidone?

You can request a quote for Clonidine and chlorthalidone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Clonidine and chlorthalidone?

Yes, KEHONG BIO provides custom synthesis services for Clonidine and chlorthalidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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