FO 152
TL;DR: FO 152 (CAS 80667-13-6) is a chemical compound with molecular formula C14H21ClFN3O7 and molecular weight 397.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S)-2-amino-3-methylbutanoate;hydrochloride
Also Known As: FO 152, 5'-O-L-Valyl-5-fluorouridine hydrochloride, 5'-o-(l-valyl)-5-fluorouridine Hydrochloride, [(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S)-2-amino-3-methylbutanoate hydrochloride
| Molecular Formula | C14H21ClFN3O7 |
|---|---|
| Molecular Weight | 397.11 g/mol |
| LogP | -1.7568 |
| Topological Polar Surface Area | 156.87 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 397.1052 |
| Heavy Atoms | 26 |
| Complexity | 752.7913 |
Chemical Identifiers
| CAS Number | 80667-13-6 |
|---|---|
| SMILES | CC(C)[C@@H](C(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O)N.Cl |
Product Overview
FO 152 (CAS 80667-13-6), with molecular formula C14H21ClFN3O7 and molecular weight 397.11 g/mol. IUPAC: [(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S)-2-amino-3-methylbutanoate;hydrochloride.
Chemical Property Profile of FO 152
Property Insights of FO 152
The XLogP value of -1.7568 indicates that FO 152 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 156.87 Ų indicates high polarity, suggesting FO 152 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, FO 152 has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of FO 152?
The CAS number of FO 152 is 80667-13-6.
What is the molecular formula of FO 152?
The molecular formula of FO 152 is C14H21ClFN3O7.
What is the molecular weight of FO 152?
The molecular weight of FO 152 is 397.11 g/mol.
Where can I buy FO 152?
You can request a quote for FO 152 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for FO 152?
Yes, KEHONG BIO provides custom synthesis services for FO 152 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.