CLOTICASONE PROPIONATE
TL;DR: CLOTICASONE PROPIONATE (CAS 80486-69-7) is a chemical compound with molecular formula C25H31ClF2O5S and molecular weight 516.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(6S,9R,10S,11S,13S,14S,16R,17R)-17-(chloromethylsulfanylcarbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Also Known As: CLOTICASONE PROPIONATE, (8xi)-17beta-{[(Chloromethyl)sulfanyl]carbonyl}-6alpha,9-difluoro-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl propanoate, [(6S,9R,10S,11S,13S,14S,16R,17R)-17-(chloromethylsulfanylcarbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate, 17-{[(Chloromethyl)sulfanyl]carbonyl}-6,9-difluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate
| Molecular Formula | C25H31ClF2O5S |
|---|---|
| Molecular Weight | 516.15 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 106.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 516.1549 |
| Heavy Atoms | 34 |
| Complexity | 986.0 |
Chemical Identifiers
| CAS Number | 80486-69-7 |
|---|---|
| SMILES | CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3(C2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCCl |
| InChIKey | MVLBCBPGBUAVJQ-ZHLGSTKJSA-N |
Product Overview
CLOTICASONE PROPIONATE (CAS 80486-69-7), with molecular formula C25H31ClF2O5S and molecular weight 516.15 g/mol. IUPAC: [(6S,9R,10S,11S,13S,14S,16R,17R)-17-(chloromethylsulfanylcarbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate.
Chemical Property Profile of CLOTICASONE PROPIONATE
Property Insights of CLOTICASONE PROPIONATE
The XLogP value of 4.2 indicates that CLOTICASONE PROPIONATE is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 106.0 Ų falls within the moderate polarity range, balancing permeability and solubility for CLOTICASONE PROPIONATE. Following Lipinski's Rule of Five, CLOTICASONE PROPIONATE has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of CLOTICASONE PROPIONATE?
The CAS number of CLOTICASONE PROPIONATE is 80486-69-7.
What is the molecular formula of CLOTICASONE PROPIONATE?
The molecular formula of CLOTICASONE PROPIONATE is C25H31ClF2O5S.
What is the molecular weight of CLOTICASONE PROPIONATE?
The molecular weight of CLOTICASONE PROPIONATE is 516.15 g/mol.
Where can I buy CLOTICASONE PROPIONATE?
You can request a quote for CLOTICASONE PROPIONATE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for CLOTICASONE PROPIONATE?
Yes, KEHONG BIO provides custom synthesis services for CLOTICASONE PROPIONATE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.