Fluticasone acetate
TL;DR: Fluticasone acetate (CAS 80474-24-4) is a chemical compound with molecular formula C24H29F3O5S and molecular weight 486.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate
Also Known As: Fluticasone acetate, 17-yl ester, Fluticasone Impurity C, Fluticasone Propionate EP Impurity C, Fluticasone Related Compound C
| Molecular Formula | C24H29F3O5S |
|---|---|
| Molecular Weight | 486.17 g/mol |
| LogP | 4.0399 |
| Topological Polar Surface Area | 80.67 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 486.1688 |
| Heavy Atoms | 33 |
| Complexity | 967.74634 |
Chemical Identifiers
| CAS Number | 80474-24-4 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCF)OC(=O)C)C)O)F)C)F |
Product Overview
Fluticasone acetate (CAS 80474-24-4), with molecular formula C24H29F3O5S and molecular weight 486.17 g/mol. IUPAC: [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate.
Chemical Property Profile of Fluticasone acetate
Property Insights of Fluticasone acetate
The XLogP value of 4.0399 indicates that Fluticasone acetate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.67 Ų falls within the moderate polarity range, balancing permeability and solubility for Fluticasone acetate. Following Lipinski's Rule of Five, Fluticasone acetate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fluticasone acetate?
The CAS number of Fluticasone acetate is 80474-24-4.
What is the molecular formula of Fluticasone acetate?
The molecular formula of Fluticasone acetate is C24H29F3O5S.
What is the molecular weight of Fluticasone acetate?
The molecular weight of Fluticasone acetate is 486.17 g/mol.
Where can I buy Fluticasone acetate?
You can request a quote for Fluticasone acetate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fluticasone acetate?
Yes, KEHONG BIO provides custom synthesis services for Fluticasone acetate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.