Mafoprazine
TL;DR: Mafoprazine (CAS 80428-29-1) is a chemical compound with molecular formula C22H28FN3O3 and molecular weight 401.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-[3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy]-3-methoxyphenyl]acetamide
Also Known As: Mafoprazine, Mafoprazina, Mafoprazinum, Mafoprazine [INN], Mafoprazinum [Latin]
| Molecular Formula | C22H28FN3O3 |
|---|---|
| Molecular Weight | 401.21 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 54.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 401.21146 |
| Heavy Atoms | 29 |
| Complexity | 502.0 |
Chemical Identifiers
| CAS Number | 80428-29-1 |
|---|---|
| SMILES | CC(=O)NC1=CC(=C(C=C1)OCCCN2CCN(CC2)C3=CC=CC=C3F)OC |
| InChIKey | PHOCQBYGUQPMIB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Mafoprazine (CAS 80428-29-1), with molecular formula C22H28FN3O3 and molecular weight 401.21 g/mol. IUPAC: N-[4-[3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy]-3-methoxyphenyl]acetamide.
Chemical Property Profile of Mafoprazine
Property Insights of Mafoprazine
The XLogP value of 3.1 indicates that Mafoprazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.0 Ų, Mafoprazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Mafoprazine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Mafoprazine?
The CAS number of Mafoprazine is 80428-29-1.
What is the molecular formula of Mafoprazine?
The molecular formula of Mafoprazine is C22H28FN3O3.
What is the molecular weight of Mafoprazine?
The molecular weight of Mafoprazine is 401.21 g/mol.
Where can I buy Mafoprazine?
You can request a quote for Mafoprazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Mafoprazine?
Yes, KEHONG BIO provides custom synthesis services for Mafoprazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.