trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane
TL;DR: trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane (CAS 80408-29-3) is a chemical compound with molecular formula C15H27N5O5 and molecular weight 357.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Also Known As: e-64, Proteinase inhibitor E 64, Thiol protease inhibitor, 6,8-Diprenylorobol, E 64 (proteinase inhibitor)
| Molecular Formula | C15H27N5O5 |
|---|---|
| Molecular Weight | 357.20 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 172.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 11 |
| Exact Mass | 357.20123 |
| Heavy Atoms | 25 |
| Complexity | 518.0 |
Chemical Identifiers
| CAS Number | 80408-29-3 |
|---|---|
| SMILES | CC(C)C[C@@H](C(=O)NCCCCN=C(N)N)NC(=O)[C@@H]1[C@H](O1)C(=O)O |
| InChIKey | LTLYEAJONXGNFG-DCAQKATOSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane (CAS 80408-29-3), with molecular formula C15H27N5O5 and molecular weight 357.20 g/mol. IUPAC: (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid.
Chemical Property Profile of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane
Property Insights of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane
The XLogP value of -0.9 indicates that trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 172.0 Ų indicates high polarity, suggesting trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane?
The CAS number of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane is 80408-29-3.
What is the molecular formula of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane?
The molecular formula of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane is C15H27N5O5.
What is the molecular weight of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane?
The molecular weight of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane is 357.20 g/mol.
Where can I buy trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane?
You can request a quote for trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane?
Yes, KEHONG BIO provides custom synthesis services for trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.