RefChem:372041 structure

RefChem:372041

TL;DR: RefChem:372041 (CAS 80305-19-7) is a chemical compound with molecular formula C20H27Cl3N2O3 and molecular weight 448.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(2-chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine;dihydrochloride

Also Known As: N-(3,4,5-Trimethoxybenzyl)-N'-(2-chlorophenyl)piperazine dihydrochloride, 1-(2-Chlorophenyl)-4-((3,4,5-trimethoxyphenyl)methyl)piperazine dihydrochloride, Piperazine, 1-(2-chlorophenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride, N-(3,4,5-trimethoxy-benzyl)-N'-(2-chlorophenyl)-piperazine dihydrochloride, 1-(2-chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine dihydrochloride

CAS: 80305-19-7
Molecular Formula C20H27Cl3N2O3
Molecular Weight 448.11 g/mol
LogP 4.5316
Topological Polar Surface Area 34.17 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 448.10873
Heavy Atoms 28
Complexity 728.22095

Chemical Identifiers

CAS Number 80305-19-7
SMILES COC1=CC(=CC(=C1OC)OC)CN2CCN(CC2)C3=CC=CC=C3Cl.Cl.Cl

Product Overview

RefChem:372041 (CAS 80305-19-7), with molecular formula C20H27Cl3N2O3 and molecular weight 448.11 g/mol. IUPAC: 1-(2-chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine;dihydrochloride.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:372041

XLogP
4.5316
TPSA (Topological Polar Surface Area)
34.17
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
28
Complexity
728.22095
Exact Mass
448.10873
Monoisotopic Mass
448.10873
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:372041

The XLogP value of 4.5316 indicates that RefChem:372041 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.17 Ų, RefChem:372041 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:372041 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:372041?

The CAS number of RefChem:372041 is 80305-19-7.

What is the molecular formula of RefChem:372041?

The molecular formula of RefChem:372041 is C20H27Cl3N2O3.

What is the molecular weight of RefChem:372041?

The molecular weight of RefChem:372041 is 448.11 g/mol.

Where can I buy RefChem:372041?

You can request a quote for RefChem:372041 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:372041?

Yes, KEHONG BIO provides custom synthesis services for RefChem:372041 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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