N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride
TL;DR: N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride (CAS 80305-12-0) is a chemical compound with molecular formula C20H26ClFN2O3 and molecular weight 396.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine;hydrochloride
Also Known As: N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride, Piperazine, 1-(4-fluorophenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, monohydrochloride, 1-(4-Fluorophenyl)-4-((3,4,5-trimethoxyphenyl)methyl)piperazine monohydrochloride, 1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine hydrochloride, 1-(4-Fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine--hydrogen chloride (1/1)
| Molecular Formula | C20H26ClFN2O3 |
|---|---|
| Molecular Weight | 396.16 g/mol |
| LogP | 3.5955 |
| Topological Polar Surface Area | 34.17 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 396.1616 |
| Heavy Atoms | 27 |
| Complexity | 709.50183 |
Chemical Identifiers
| CAS Number | 80305-12-0 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)CN2CCN(CC2)C3=CC=C(C=C3)F.Cl |
Product Overview
N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride (CAS 80305-12-0), with molecular formula C20H26ClFN2O3 and molecular weight 396.16 g/mol. IUPAC: 1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine;hydrochloride.
Chemical Property Profile of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride
Property Insights of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride
The XLogP value of 3.5955 indicates that N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.17 Ų, N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride?
The CAS number of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride is 80305-12-0.
What is the molecular formula of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride?
The molecular formula of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride is C20H26ClFN2O3.
What is the molecular weight of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride?
The molecular weight of N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride is 396.16 g/mol.
Where can I buy N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride?
You can request a quote for N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for N-(3,4,5-Trimethoxybenzyl)-N'-(4-fluorophenyl)piperazine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.