Amsacrine Lactate structure

Amsacrine Lactate

TL;DR: Amsacrine Lactate (CAS 80277-11-8) is a chemical compound with molecular formula C24H25N3O6S and molecular weight 483.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide;2-hydroxypropanoic acid

Also Known As: Amsacrine lactate, m-AMSA lactate, AMSA, N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide, Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)-, mono(2-hydroxypropanoate)

CAS: 80277-11-8
Molecular Formula C24H25N3O6S
Molecular Weight 483.15 g/mol
LogP 3.96
Topological Polar Surface Area 146.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 9
Rotatable Bonds 6
Exact Mass 483.1464
Heavy Atoms 34
Complexity 660.0

Chemical Identifiers

CAS Number 80277-11-8
SMILES CC(C(=O)O)O.COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
InChIKey NYGZSXVEKMITFN-UHFFFAOYSA-N

Product Overview

Amsacrine Lactate (CAS 80277-11-8), with molecular formula C24H25N3O6S and molecular weight 483.15 g/mol. IUPAC: N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide;2-hydroxypropanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Amsacrine Lactate

XLogP
3.96
TPSA (Topological Polar Surface Area)
146.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
9
Rotatable Bonds
6
Heavy Atoms
34
Complexity
660.0
Exact Mass
483.1464
Monoisotopic Mass
483.1464
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Amsacrine Lactate

The XLogP value of 3.96 indicates that Amsacrine Lactate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 146.0 Ų indicates high polarity, suggesting Amsacrine Lactate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amsacrine Lactate has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Amsacrine Lactate?

The CAS number of Amsacrine Lactate is 80277-11-8.

What is the molecular formula of Amsacrine Lactate?

The molecular formula of Amsacrine Lactate is C24H25N3O6S.

What is the molecular weight of Amsacrine Lactate?

The molecular weight of Amsacrine Lactate is 483.15 g/mol.

Where can I buy Amsacrine Lactate?

You can request a quote for Amsacrine Lactate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Amsacrine Lactate?

Yes, KEHONG BIO provides custom synthesis services for Amsacrine Lactate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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