10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one
TL;DR: 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one (CAS 80271-11-0) is a chemical compound with molecular formula C16H12N2O and molecular weight 248.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-methyl-5H-indolo[3,2-b]quinolin-11-one
Also Known As: 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one, 10-methyl-5H-indolo[3,2-b]quinolin-11-one, 5,10-Dihydro-10-methyl-11H-quindolin-11-one, NCI60_003234, 11H-Quindolin-11-one, 5,10-dihydro-10-methyl-
| Molecular Formula | C16H12N2O |
|---|---|
| Molecular Weight | 248.09 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 34.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 248.09496 |
| Heavy Atoms | 19 |
| Complexity | 383.0 |
Chemical Identifiers
| CAS Number | 80271-11-0 |
|---|---|
| SMILES | CN1C2=CC=CC=C2C3=C1C(=O)C4=CC=CC=C4N3 |
| InChIKey | QVDRLIBKQUXZIZ-UHFFFAOYSA-N |
Product Overview
10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one (CAS 80271-11-0), with molecular formula C16H12N2O and molecular weight 248.09 g/mol. IUPAC: 10-methyl-5H-indolo[3,2-b]quinolin-11-one.
Chemical Property Profile of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one
Property Insights of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one
The XLogP value of 3.4 indicates that 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.0 Ų, 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one?
The CAS number of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one is 80271-11-0.
What is the molecular formula of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one?
The molecular formula of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one is C16H12N2O.
What is the molecular weight of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one?
The molecular weight of 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one is 248.09 g/mol.
Where can I buy 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one?
You can request a quote for 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one?
Yes, KEHONG BIO provides custom synthesis services for 10-Methyl-5,10-dihydro-11H-indolo(3,2-b)quinolin-11-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.