(E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine structure

(E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine

TL;DR: (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine (CAS 80222-87-3) is a chemical compound with molecular formula C20H23ClN4O and molecular weight 370.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[(2-amino-5-chlorophenyl)-phenylmethylidene]amino]-1-(4-methylpiperazin-1-yl)ethanone

Also Known As: (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine, Piperazine, 1-((((2-amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methyl-, (E)-, 2-[[(2-amino-5-chlorophenyl)-phenylmethylidene]amino]-1-(4-methylpiperazin-1-yl)ethanone

CAS: 80222-87-3
Molecular Formula C20H23ClN4O
Molecular Weight 370.16 g/mol
LogP 2.5336
Topological Polar Surface Area 61.93 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 370.15604
Heavy Atoms 26
Complexity 798.71344

Chemical Identifiers

CAS Number 80222-87-3
SMILES CN1CCN(CC1)C(=O)CN=C(C2=CC=CC=C2)C3=C(C=CC(=C3)Cl)N

Product Overview

(E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine (CAS 80222-87-3), with molecular formula C20H23ClN4O and molecular weight 370.16 g/mol. IUPAC: 2-[[(2-amino-5-chlorophenyl)-phenylmethylidene]amino]-1-(4-methylpiperazin-1-yl)ethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine

XLogP
2.5336
TPSA (Topological Polar Surface Area)
61.93
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
26
Complexity
798.71344
Exact Mass
370.15604
Monoisotopic Mass
370.15604
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine

The XLogP value of 2.5336 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine. The TPSA of 61.93 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine. Following Lipinski's Rule of Five, (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine?

The CAS number of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine is 80222-87-3.

What is the molecular formula of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine?

The molecular formula of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine is C20H23ClN4O.

What is the molecular weight of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine?

The molecular weight of (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine is 370.16 g/mol.

Where can I buy (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine?

You can request a quote for (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine?

Yes, KEHONG BIO provides custom synthesis services for (E)-1-((((2-Amino-5-chlorophenyl)phenylmethylene)amino)acetyl)-4-methylpiperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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