Aopta structure

Aopta

TL;DR: Aopta (CAS 80186-83-0) is a chemical compound with molecular formula C20H26N10O12P2S and molecular weight 694.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl] [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[[hydroxy(oxidanyl)(18O)phosphinothioyl]oxymethyl]oxolan-2-yl]methyl hydrogen phosphate

Also Known As: AOPTA, Adenyl-5'-O-phosphorothioate-(3'-5')adenosine, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl] [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[[hydroxy(oxidanyl)(18O)phosphinothioyl]oxymethyl]oxolan-2-yl]methyl hydrogen phosphate, Adenosine, 5'-O-(hydroxyhydroxy-18O-phosphinothioyl)adenylyl-(3'-5')-, (S)-, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl] [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[[hydroxy(oxidanyl)phosphinothioyl]oxymethyl]oxolan-2-yl]methyl hydrogen phosphate

CAS: 80186-83-0
Molecular Formula C20H26N10O12P2S
Molecular Weight 694.10 g/mol
LogP -2.3589
Topological Polar Surface Area 323.84 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 18
Rotatable Bonds 10
Exact Mass 694.097
Heavy Atoms 45
Complexity 1808.5052

Chemical Identifiers

CAS Number 80186-83-0
SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)COP(=S)(O)[18OH])O)N

Product Overview

Aopta (CAS 80186-83-0), with molecular formula C20H26N10O12P2S and molecular weight 694.10 g/mol. IUPAC: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl] [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[[hydroxy(oxidanyl)(18O)phosphinothioyl]oxymethyl]oxolan-2-yl]methyl hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Aopta

XLogP
-2.3589
TPSA (Topological Polar Surface Area)
323.84
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
18
Rotatable Bonds
10
Heavy Atoms
45
Complexity
1808.5052
Exact Mass
694.097
Monoisotopic Mass
694.097
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Aopta

The XLogP value of -2.3589 indicates that Aopta is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 323.84 Ų indicates high polarity, suggesting Aopta may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Aopta has 8 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Aopta?

The CAS number of Aopta is 80186-83-0.

What is the molecular formula of Aopta?

The molecular formula of Aopta is C20H26N10O12P2S.

What is the molecular weight of Aopta?

The molecular weight of Aopta is 694.10 g/mol.

Where can I buy Aopta?

You can request a quote for Aopta directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Aopta?

Yes, KEHONG BIO provides custom synthesis services for Aopta and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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