(2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol
TL;DR: (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol (CAS 80100-26-1) is a chemical compound with molecular formula C12H8ClF2NO and molecular weight 255.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2-chloro-3-pyridinyl)-(2,4-difluorophenyl)methanol
Also Known As: 2-Chloro-alpha-(2,4-difluorophenyl)-3-pyridinemethanol, 3-Pyridinemethanol, 2-chloro-alpha-(2,4-difluorophenyl)-, (2-chloropyridin-3-yl)-(2,4-difluorophenyl)methanol, (2-CHLOROPYRIDIN-3-YL)(2,4-DIFLUOROPHENYL)METHANOL, RefChem:1049675
| Molecular Formula | C12H8ClF2NO |
|---|---|
| Molecular Weight | 255.03 g/mol |
| LogP | 3.0949 |
| Topological Polar Surface Area | 33.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 255.02625 |
| Heavy Atoms | 17 |
| Complexity | 547.7789 |
Chemical Identifiers
| CAS Number | 80100-26-1 |
|---|---|
| SMILES | C1=CC(=C(N=C1)Cl)C(C2=C(C=C(C=C2)F)F)O |
Product Overview
(2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol (CAS 80100-26-1), with molecular formula C12H8ClF2NO and molecular weight 255.03 g/mol. IUPAC: (2-chloro-3-pyridinyl)-(2,4-difluorophenyl)methanol.
Chemical Property Profile of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol
Property Insights of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol
The XLogP value of 3.0949 indicates that (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 33.12 Ų, (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol?
The CAS number of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol is 80100-26-1.
What is the molecular formula of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol?
The molecular formula of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol is C12H8ClF2NO.
What is the molecular weight of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol?
The molecular weight of (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol is 255.03 g/mol.
Where can I buy (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol?
You can request a quote for (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol?
Yes, KEHONG BIO provides custom synthesis services for (2-Chloropyridin-3-yl)(2,4-difluorophenyl)methanol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.