Tecastemizole
TL;DR: Tecastemizole (CAS 80036-97-1) is a chemical compound with molecular formula C19H21FN4 and molecular weight 324.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
Also Known As: Tecastemizole, Norastemizole, Soltara, Tecastemizol, tecastemizolum
| Molecular Formula | C19H21FN4 |
|---|---|
| Molecular Weight | 324.18 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 41.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 324.17502 |
| Heavy Atoms | 24 |
| Complexity | 393.0 |
Chemical Identifiers
| CAS Number | 80036-97-1 |
|---|---|
| SMILES | C1CNCCC1NC2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F |
| InChIKey | SFOVDSLXFUGAIV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tecastemizole (CAS 80036-97-1), with molecular formula C19H21FN4 and molecular weight 324.18 g/mol. IUPAC: 1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine.
Chemical Property Profile of Tecastemizole
Property Insights of Tecastemizole
The XLogP value of 3.6 indicates that Tecastemizole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.9 Ų, Tecastemizole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tecastemizole has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tecastemizole?
The CAS number of Tecastemizole is 80036-97-1.
What is the molecular formula of Tecastemizole?
The molecular formula of Tecastemizole is C19H21FN4.
What is the molecular weight of Tecastemizole?
The molecular weight of Tecastemizole is 324.18 g/mol.
Where can I buy Tecastemizole?
You can request a quote for Tecastemizole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tecastemizole?
Yes, KEHONG BIO provides custom synthesis services for Tecastemizole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.