Nemadipine B
TL;DR: Nemadipine B (CAS 79925-38-5) is a chemical compound with molecular formula C19H21Cl2NO4 and molecular weight 397.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
diethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Nemadipine B, Nemadipine-B, Felodipine EP Impurity C, Felodipine Impurity C, diethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
| Molecular Formula | C19H21Cl2NO4 |
|---|---|
| Molecular Weight | 397.08 g/mol |
| LogP | 4.3544 |
| Topological Polar Surface Area | 64.63 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 397.08478 |
| Heavy Atoms | 26 |
| Complexity | 758.7289 |
Chemical Identifiers
| CAS Number | 79925-38-5 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OCC)C)C |
Product Overview
Nemadipine B (CAS 79925-38-5), with molecular formula C19H21Cl2NO4 and molecular weight 397.08 g/mol. IUPAC: diethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Nemadipine B
Property Insights of Nemadipine B
The XLogP value of 4.3544 indicates that Nemadipine B is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.63 Ų falls within the moderate polarity range, balancing permeability and solubility for Nemadipine B. Following Lipinski's Rule of Five, Nemadipine B has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nemadipine B?
The CAS number of Nemadipine B is 79925-38-5.
What is the molecular formula of Nemadipine B?
The molecular formula of Nemadipine B is C19H21Cl2NO4.
What is the molecular weight of Nemadipine B?
The molecular weight of Nemadipine B is 397.08 g/mol.
Where can I buy Nemadipine B?
You can request a quote for Nemadipine B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nemadipine B?
Yes, KEHONG BIO provides custom synthesis services for Nemadipine B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.