Amlodipine Impurity 28
TL;DR: Amlodipine Impurity 28 (CAS 79781-21-8) is a chemical compound with molecular formula C18H20ClNO5 and molecular weight 365.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-O-ethyl 5-O-methyl 4-(2-chlorophenyl)-2-(hydroxymethyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Amlodipine Impurity 28, Amlodipine Impurity 86, Amlodipine Impurity 63, 4-(2-Chlorophenyl)-1,4-dihydro-2-(hydroxymethyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester, 3-ethyl 5-methyl 4-(2-chlorophenyl)-2-(hydroxymethyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
| Molecular Formula | C18H20ClNO5 |
|---|---|
| Molecular Weight | 365.10 g/mol |
| LogP | 2.2833 |
| Topological Polar Surface Area | 84.86 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 365.103 |
| Heavy Atoms | 25 |
| Complexity | 753.58826 |
Chemical Identifiers
| CAS Number | 79781-21-8 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)CO |
Product Overview
Amlodipine Impurity 28 (CAS 79781-21-8), with molecular formula C18H20ClNO5 and molecular weight 365.10 g/mol. IUPAC: 3-O-ethyl 5-O-methyl 4-(2-chlorophenyl)-2-(hydroxymethyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Amlodipine Impurity 28
Property Insights of Amlodipine Impurity 28
The XLogP value of 2.2833 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Amlodipine Impurity 28. The TPSA of 84.86 Ų falls within the moderate polarity range, balancing permeability and solubility for Amlodipine Impurity 28. Following Lipinski's Rule of Five, Amlodipine Impurity 28 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amlodipine Impurity 28?
The CAS number of Amlodipine Impurity 28 is 79781-21-8.
What is the molecular formula of Amlodipine Impurity 28?
The molecular formula of Amlodipine Impurity 28 is C18H20ClNO5.
What is the molecular weight of Amlodipine Impurity 28?
The molecular weight of Amlodipine Impurity 28 is 365.10 g/mol.
Where can I buy Amlodipine Impurity 28?
You can request a quote for Amlodipine Impurity 28 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amlodipine Impurity 28?
Yes, KEHONG BIO provides custom synthesis services for Amlodipine Impurity 28 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.