Trimethoprim sulfamethizole
TL;DR: Trimethoprim sulfamethizole (CAS 79735-35-6) is a chemical compound with molecular formula C23H28N8O5S2 and molecular weight 560.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Also Known As: Trimethoprim sulfamethizole, Sulfamethizole mixture with trimethoprim, Sulfamethizole mixture with trimethoprim, SID:134224613, 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
| Molecular Formula | C23H28N8O5S2 |
|---|---|
| Molecular Weight | 560.16 g/mol |
| LogP | 2.49 |
| Topological Polar Surface Area | 240.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 8 |
| Exact Mass | 560.1624 |
| Heavy Atoms | 38 |
| Complexity | 655.0 |
Chemical Identifiers
| CAS Number | 79735-35-6 |
|---|---|
| SMILES | CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N.COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N |
| InChIKey | ZKSSBLPBDVQKCH-UHFFFAOYSA-N |
Product Overview
Trimethoprim sulfamethizole (CAS 79735-35-6), with molecular formula C23H28N8O5S2 and molecular weight 560.16 g/mol. IUPAC: 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine.
Chemical Property Profile of Trimethoprim sulfamethizole
Property Insights of Trimethoprim sulfamethizole
The XLogP value of 2.49 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trimethoprim sulfamethizole. The TPSA of 240.0 Ų indicates high polarity, suggesting Trimethoprim sulfamethizole may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Trimethoprim sulfamethizole has 4 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Trimethoprim sulfamethizole?
The CAS number of Trimethoprim sulfamethizole is 79735-35-6.
What is the molecular formula of Trimethoprim sulfamethizole?
The molecular formula of Trimethoprim sulfamethizole is C23H28N8O5S2.
What is the molecular weight of Trimethoprim sulfamethizole?
The molecular weight of Trimethoprim sulfamethizole is 560.16 g/mol.
Where can I buy Trimethoprim sulfamethizole?
You can request a quote for Trimethoprim sulfamethizole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Trimethoprim sulfamethizole?
Yes, KEHONG BIO provides custom synthesis services for Trimethoprim sulfamethizole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.