sertraline mandelate structure

sertraline mandelate

TL;DR: sertraline mandelate (CAS 79617-97-3) is a chemical compound with molecular formula C25H25Cl2NO3 and molecular weight 457.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;(2R)-2-hydroxy-2-phenylacetic acid

Also Known As: sertraline mandelate, Benzeneacetic acid, alpha-hydroxy-, (alphaR)-, compd. with (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine (1:1), 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)-, (alphaR)-alpha-hydroxybenzeneacetate, 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S-cis)-, (R)-alpha-hydroxybenzeneacetate, Benzeneacetic acid, alpha-hydroxy-, (R)-, compd. with (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine (1:1)

CAS: 79617-97-3
Molecular Formula C25H25Cl2NO3
Molecular Weight 457.12 g/mol
LogP 5.9842
Topological Polar Surface Area 69.56 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 457.12115
Heavy Atoms 31
Complexity 1026.2855

Chemical Identifiers

CAS Number 79617-97-3
SMILES CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.C1=CC=C(C=C1)[C@H](C(=O)O)O

Product Overview

sertraline mandelate (CAS 79617-97-3), with molecular formula C25H25Cl2NO3 and molecular weight 457.12 g/mol. IUPAC: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;(2R)-2-hydroxy-2-phenylacetic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of sertraline mandelate

XLogP
5.9842
TPSA (Topological Polar Surface Area)
69.56
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
31
Complexity
1026.2855
Exact Mass
457.12115
Monoisotopic Mass
457.12115
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of sertraline mandelate

The XLogP value of 5.9842 indicates that sertraline mandelate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 69.56 Ų falls within the moderate polarity range, balancing permeability and solubility for sertraline mandelate. Following Lipinski's Rule of Five, sertraline mandelate has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of sertraline mandelate?

The CAS number of sertraline mandelate is 79617-97-3.

What is the molecular formula of sertraline mandelate?

The molecular formula of sertraline mandelate is C25H25Cl2NO3.

What is the molecular weight of sertraline mandelate?

The molecular weight of sertraline mandelate is 457.12 g/mol.

Where can I buy sertraline mandelate?

You can request a quote for sertraline mandelate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for sertraline mandelate?

Yes, KEHONG BIO provides custom synthesis services for sertraline mandelate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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