(+)-Makomakine
TL;DR: (+)-Makomakine (CAS 79559-56-1) is a chemical compound with molecular formula C20H26N2 and molecular weight 294.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[[(1S,2R,5S)-4,4-dimethyl-8-methylidene-3-azabicyclo[3.3.1]nonan-2-yl]methyl]-1H-indole
Also Known As: (+)-Makomakine, ICCB6_000292, J1.839.350F, 3-{[(1S,2R,5S)-4,4-dimethyl-8-methylidene-3-azabicyclo[3.3.1]nonan-2-yl]methyl}-1H-indole, rel-3-{[(1R,2S,5R)-4,4-dimethyl-8-methylene-3-azabicyclo[3.3.1]non-2-yl]methyl}-1H-indole
| Molecular Formula | C20H26N2 |
|---|---|
| Molecular Weight | 294.21 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 27.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 294.2096 |
| Heavy Atoms | 22 |
| Complexity | 441.0 |
Chemical Identifiers
| CAS Number | 79559-56-1 |
|---|---|
| SMILES | CC1([C@H]2CCC(=C)[C@H](C2)[C@H](N1)CC3=CNC4=CC=CC=C43)C |
| InChIKey | GELMCGOPWNCDHN-VDZJLULYSA-N |
Product Overview
(+)-Makomakine (CAS 79559-56-1), with molecular formula C20H26N2 and molecular weight 294.21 g/mol. IUPAC: 3-[[(1S,2R,5S)-4,4-dimethyl-8-methylidene-3-azabicyclo[3.3.1]nonan-2-yl]methyl]-1H-indole.
Chemical Property Profile of (+)-Makomakine
Property Insights of (+)-Makomakine
The XLogP value of 3.9 indicates that (+)-Makomakine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 27.8 Ų, (+)-Makomakine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (+)-Makomakine has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Makomakine?
The CAS number of (+)-Makomakine is 79559-56-1.
What is the molecular formula of (+)-Makomakine?
The molecular formula of (+)-Makomakine is C20H26N2.
What is the molecular weight of (+)-Makomakine?
The molecular weight of (+)-Makomakine is 294.21 g/mol.
Where can I buy (+)-Makomakine?
You can request a quote for (+)-Makomakine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Makomakine?
Yes, KEHONG BIO provides custom synthesis services for (+)-Makomakine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.