Azelastine Hydrochloride
TL;DR: Azelastine Hydrochloride (CAS 79307-93-0) is a chemical compound with molecular formula C22H25Cl2N3O and molecular weight 417.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one;hydrochloride
Also Known As: AZELASTINE HYDROCHLORIDE, AZELASTINE HCl, Astelin, Optivar, azelastine
| Molecular Formula | C22H25Cl2N3O |
|---|---|
| Molecular Weight | 417.14 g/mol |
| LogP | 4.72 |
| Topological Polar Surface Area | 35.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 417.13748 |
| Heavy Atoms | 28 |
| Complexity | 558.0 |
Chemical Identifiers
| CAS Number | 79307-93-0 |
|---|---|
| SMILES | CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl |
| InChIKey | YEJAJYAHJQIWNU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Azelastine Hydrochloride (CAS 79307-93-0), with molecular formula C22H25Cl2N3O and molecular weight 417.14 g/mol. IUPAC: 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one;hydrochloride.
Chemical Property Profile of Azelastine Hydrochloride
Property Insights of Azelastine Hydrochloride
The XLogP value of 4.72 indicates that Azelastine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.9 Ų, Azelastine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Azelastine Hydrochloride has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Azelastine Hydrochloride?
The CAS number of Azelastine Hydrochloride is 79307-93-0.
What is the molecular formula of Azelastine Hydrochloride?
The molecular formula of Azelastine Hydrochloride is C22H25Cl2N3O.
What is the molecular weight of Azelastine Hydrochloride?
The molecular weight of Azelastine Hydrochloride is 417.14 g/mol.
Where can I buy Azelastine Hydrochloride?
You can request a quote for Azelastine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Azelastine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Azelastine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.