Krm-iii
TL;DR: Krm-iii (CAS 79220-94-3) is a chemical compound with molecular formula C15H12N2S and molecular weight 252.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,5-diphenyl-1H-imidazole-2-thione
Also Known As: KRM-III, ChemDiv3_012382, 1,4-diphenyl-1,3-dihydro-2H-imidazole-2-thione, 3,5-diphenyl-1H-imidazole-2-thione, 1,3-Dihydro-1,4-diphenyl-2H-imidazole-2-thione
| Molecular Formula | C15H12N2S |
|---|---|
| Molecular Weight | 252.07 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 47.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 252.07211 |
| Heavy Atoms | 18 |
| Complexity | 338.0 |
Chemical Identifiers
| CAS Number | 79220-94-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=CN(C(=S)N2)C3=CC=CC=C3 |
| InChIKey | QKOAQVKXZJFMET-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Krm-iii (CAS 79220-94-3), with molecular formula C15H12N2S and molecular weight 252.07 g/mol. IUPAC: 3,5-diphenyl-1H-imidazole-2-thione.
Chemical Property Profile of Krm-iii
Property Insights of Krm-iii
The XLogP value of 3.1 indicates that Krm-iii is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.4 Ų, Krm-iii exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Krm-iii has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Krm-iii?
The CAS number of Krm-iii is 79220-94-3.
What is the molecular formula of Krm-iii?
The molecular formula of Krm-iii is C15H12N2S.
What is the molecular weight of Krm-iii?
The molecular weight of Krm-iii is 252.07 g/mol.
Where can I buy Krm-iii?
You can request a quote for Krm-iii directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Krm-iii?
Yes, KEHONG BIO provides custom synthesis services for Krm-iii and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.