4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide
TL;DR: 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide (CAS 791786-63-5) is a chemical compound with molecular formula C20H17FN4OS and molecular weight 380.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide
Also Known As: 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide, AF-399/42928004, 4-[5-fluoro-2-(pyridin-2-yl)-1H-indol-3-yl]-N-(1,3-thiazol-2-yl)butanamide, 4-[5-fluoro-2-(2-pyridinyl)-1H-indol-3-yl]-N-(1,3-thiazol-2-yl)butanamide, 4-(5-fluoro-2-(2-pyridyl)indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide
| Molecular Formula | C20H17FN4OS |
|---|---|
| Molecular Weight | 380.11 g/mol |
| LogP | 4.7869 |
| Topological Polar Surface Area | 70.67 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 380.11072 |
| Heavy Atoms | 27 |
| Complexity | 1060.4874 |
Chemical Identifiers
| CAS Number | 791786-63-5 |
|---|---|
| SMILES | C1=CC=NC(=C1)C2=C(C3=C(N2)C=CC(=C3)F)CCCC(=O)NC4=NC=CS4 |
Product Overview
4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide (CAS 791786-63-5), with molecular formula C20H17FN4OS and molecular weight 380.11 g/mol. IUPAC: 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide.
Chemical Property Profile of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide
Property Insights of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide
The XLogP value of 4.7869 indicates that 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.67 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide. Following Lipinski's Rule of Five, 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide?
The CAS number of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide is 791786-63-5.
What is the molecular formula of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide?
The molecular formula of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide is C20H17FN4OS.
What is the molecular weight of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide?
The molecular weight of 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide is 380.11 g/mol.
Where can I buy 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide?
You can request a quote for 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide?
Yes, KEHONG BIO provides custom synthesis services for 4-(5-fluoro-2-pyridin-2-yl-1H-indol-3-yl)-N-(1,3-thiazol-2-yl)butanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.