9-Fluorocortisone
TL;DR: 9-Fluorocortisone (CAS 79-60-7) is a chemical compound with molecular formula C21H27FO5 and molecular weight 378.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,10S,13S,14S,17R)-9-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
Also Known As: 9-Fluorocortisone, Pregn-4-ene-3,11,20-trione,9-fluoro-17,21-dihydroxy-, (8S,10S,13S,14S,17R)-9-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
| Molecular Formula | C21H27FO5 |
|---|---|
| Molecular Weight | 378.18 g/mol |
| LogP | 2.0819 |
| Topological Polar Surface Area | 91.67 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.18427 |
| Heavy Atoms | 27 |
| Complexity | 774.5336 |
Chemical Identifiers
| CAS Number | 79-60-7 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]3C2(C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)F |
Product Overview
9-Fluorocortisone (CAS 79-60-7), with molecular formula C21H27FO5 and molecular weight 378.18 g/mol. IUPAC: (8S,10S,13S,14S,17R)-9-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione.
Chemical Property Profile of 9-Fluorocortisone
Property Insights of 9-Fluorocortisone
The XLogP value of 2.0819 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 9-Fluorocortisone. The TPSA of 91.67 Ų falls within the moderate polarity range, balancing permeability and solubility for 9-Fluorocortisone. Following Lipinski's Rule of Five, 9-Fluorocortisone has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 9-Fluorocortisone?
The CAS number of 9-Fluorocortisone is 79-60-7.
What is the molecular formula of 9-Fluorocortisone?
The molecular formula of 9-Fluorocortisone is C21H27FO5.
What is the molecular weight of 9-Fluorocortisone?
The molecular weight of 9-Fluorocortisone is 378.18 g/mol.
Where can I buy 9-Fluorocortisone?
You can request a quote for 9-Fluorocortisone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 9-Fluorocortisone?
Yes, KEHONG BIO provides custom synthesis services for 9-Fluorocortisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.