Cilastatin structure

Cilastatin

TL;DR: Cilastatin (CAS 78852-98-9) is a chemical compound with molecular formula C16H26N2O5S and molecular weight 358.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-7-(2-amino-2-carboxyethyl)sulfanyl-2-[(2,2-dimethylcyclopropanecarbonyl)amino]hept-2-enoic acid

Also Known As: Cilastatin, E-Cilastatin Acid, 7-((2-Amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl)carbonyl)amino)-2-heptenoic acid, (E)-7-(2-amino-2-carboxyethyl)sulfanyl-2-[(2,2-dimethylcyclopropanecarbonyl)amino]hept-2-enoic acid, 2-Heptenoic acid, 7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl)carbonyl)amino)-

CAS: 78852-98-9
Molecular Formula C16H26N2O5S
Molecular Weight 358.16 g/mol
LogP 1.4326
Topological Polar Surface Area 129.72 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 5
Rotatable Bonds 11
Exact Mass 358.15625
Heavy Atoms 24
Complexity 518.59717

Chemical Identifiers

CAS Number 78852-98-9
SMILES CC1(CC1C(=O)N/C(=C/CCCCSCC(C(=O)O)N)/C(=O)O)C

Product Overview

Cilastatin (CAS 78852-98-9), with molecular formula C16H26N2O5S and molecular weight 358.16 g/mol. IUPAC: (E)-7-(2-amino-2-carboxyethyl)sulfanyl-2-[(2,2-dimethylcyclopropanecarbonyl)amino]hept-2-enoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Cilastatin

XLogP
1.4326
TPSA (Topological Polar Surface Area)
129.72
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
5
Rotatable Bonds
11
Heavy Atoms
24
Complexity
518.59717
Exact Mass
358.15625
Monoisotopic Mass
358.15625
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cilastatin

The XLogP value of 1.4326 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Cilastatin. The TPSA of 129.72 Ų falls within the moderate polarity range, balancing permeability and solubility for Cilastatin. Following Lipinski's Rule of Five, Cilastatin has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cilastatin?

The CAS number of Cilastatin is 78852-98-9.

What is the molecular formula of Cilastatin?

The molecular formula of Cilastatin is C16H26N2O5S.

What is the molecular weight of Cilastatin?

The molecular weight of Cilastatin is 358.16 g/mol.

Where can I buy Cilastatin?

You can request a quote for Cilastatin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cilastatin?

Yes, KEHONG BIO provides custom synthesis services for Cilastatin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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