Norbuprenorphine
TL;DR: Norbuprenorphine (CAS 78715-23-8) is a chemical compound with molecular formula C25H35NO4 and molecular weight 413.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,2S,6R,14R,15R,16R)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Also Known As: Norbuprenorphine, N-Desalkylbuprenorphine, Des(cyclopropylmethyl)buprenorphine, Buprenorphine EP Impurity B, Epitope ID:2270796
| Molecular Formula | C25H35NO4 |
|---|---|
| Molecular Weight | 413.26 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 71.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 413.25662 |
| Heavy Atoms | 30 |
| Complexity | 752.0 |
Chemical Identifiers
| CAS Number | 78715-23-8 |
|---|---|
| SMILES | C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN[C@@H]3CC6=C5C(=C(C=C6)O)O4)OC)(C(C)(C)C)O |
| InChIKey | YOYLLRBMGQRFTN-IOMBULRVSA-N |
Product Overview
Norbuprenorphine (CAS 78715-23-8), with molecular formula C25H35NO4 and molecular weight 413.26 g/mol. IUPAC: (1S,2S,6R,14R,15R,16R)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol.
Chemical Property Profile of Norbuprenorphine
Property Insights of Norbuprenorphine
The XLogP value of 3.8 indicates that Norbuprenorphine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Norbuprenorphine. Following Lipinski's Rule of Five, Norbuprenorphine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Norbuprenorphine?
The CAS number of Norbuprenorphine is 78715-23-8.
What is the molecular formula of Norbuprenorphine?
The molecular formula of Norbuprenorphine is C25H35NO4.
What is the molecular weight of Norbuprenorphine?
The molecular weight of Norbuprenorphine is 413.26 g/mol.
Where can I buy Norbuprenorphine?
You can request a quote for Norbuprenorphine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Norbuprenorphine?
Yes, KEHONG BIO provides custom synthesis services for Norbuprenorphine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.